Priligy Tablets

From: £25.99

PharmaBee offers Priligy® (Dapoxetine) for the treatment of premature ejaculation (PE) in adult men aged 18 to 64. Following a secure online consultation reviewed by a our team, treatment may be approved where clinically appropriate and delivered discreetly to your door.

Priligy is currently the only medicine licensed in the UK specifically for the treatment of premature ejaculation. It is a short-acting SSRI taken one to three hours before anticipated sexual activity, designed for on-demand use rather than continuous daily dosing.

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Additional information

Quantity

12, 3, 6

Strength

30mg, 60mg

Overview

Content Written by:

Hanifa Tai
Role: Pharmacist & Content Writer
GPhC Number: 2074961
Content Published: 01/04/2026
Next Review: 01/04/2027

Medically Reviewed by:

Farzin Ghayedy
Role: Pharmacist
GPhC Number: 2218065
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Description

What Is Priligy?

Priligy contains Dapoxetine, a short-acting selective serotonin reuptake inhibitor (SSRI). It was specifically developed for the on-demand treatment of premature ejaculation. Unlike traditional SSRIs that are taken daily for mood disorders, Priligy is taken one to three hours before anticipated sexual activity. It is not intended for continuous daily use.

Dapoxetine works by increasing serotonin levels in the nervous system. By enhancing serotonin signalling in pathways that regulate the ejaculatory reflex, Priligy can delay ejaculation, increase perceived control, reduce distress associated with rapid ejaculation, and improve overall sexual satisfaction.

How Effective Is Priligy?

Clinical trials have demonstrated that Priligy significantly increases intravaginal ejaculatory latency time (IELT), improves subjective control over ejaculation, reduces personal distress, and improves satisfaction for patients and partners. Many men report benefit from the first dose. However, individual response varies. Priligy does not permanently cure premature ejaculation — its effect is present when taken and diminishes after the medicine is cleared from the body.

Dosage and Administration

Priligy is available as 30mg tablets and 60mg tablets. The recommended starting dose is 30mg, taken one to three hours before anticipated sexual activity. If response is inadequate and side effects are tolerable, the dose may be increased to 60mg following clinical review.

  • Do not take more than one tablet within 24 hours
  • Do not take daily
  • Swallow whole with water

Who Should Not Take Priligy?

Priligy is not suitable for all patients. It should not be used in men who:

  • Have significant heart failure or certain cardiac rhythm disorders
  • Have a history of fainting related to blood pressure changes
  • Have moderate or severe liver impairment
  • Have a history of bipolar disorder or mania
  • Are currently taking medicines that significantly affect serotonin levels
  • Have a history of seizures

Alcohol and Priligy

Alcohol must be avoided when taking Priligy. Combining alcohol with Dapoxetine increases the risk of dizziness, fainting, impaired coordination, and injury. Do not consume alcohol on the day you take this medication.

Drug Interactions

Priligy must not be taken with certain medications, including other SSRIs or SNRIs, monoamine oxidase inhibitors (MAOIs), certain antipsychotic medicines, some migraine treatments (triptans), certain antibiotics or antifungals, and St John’s Wort. In some cases, Priligy may be alongside erectile dysfunction treatments such as Cialis or Viagra but this requires careful assessment.

FAQ

Does Priligy work from the first dose?

Many men notice improvement from the first dose. However, response varies.

Can I take it every day?

No. Priligy is taken on demand and not more than once in 24 hours.

Does it treat erectile dysfunction?

No. Priligy is licensed specifically for premature ejaculation. If you experience erectile dysfunction, separate assessment may be required.

Will it affect fertility?

Priligy does not affect sperm production or long-term fertility.

What if it does not work for me?

Your prescriber may review dosage or advise alternative approaches, including behavioural techniques or GP referral.

Can Priligy be taken with erectile dysfunction medication?

In certain cases, Priligy may be used alongside PDE5 inhibitors such as Viagra or Cialis. However, combining these medicines can increase the risk of low blood pressure and dizziness. This combination should only be used under medical supervision.

Side Effects

Common Side Effects

Priligy is usually well tolerated but, as with all medicines, may cause side effects. Common side effects include:

  • Nausea
  • Dizziness
  • Headache
  • Diarrhoea
  • Insomnia

These are usually mild and are often reduced with continued use.

Dizziness and Postural Hypotension

Priligy may lower blood pressure when standing suddenly, which can lead to dizziness or fainting. To reduce risk:

  • Take the tablet while sitting or lying down
  • Swallow with at least one full glass of water
  • Stand up slowly
  • Avoid alcohol

If you feel light-headed, lie down immediately and raise your legs. Seek medical advice if symptoms persist.

Serious Side Effects — Seek Urgent Medical Attention

Stop treatment and seek urgent medical attention if you experience:

  • Seizures
  • Significant mood changes
  • Loss of consciousness
  • Palpitations

You should not drive or operate machinery if you feel dizzy or light-headed after taking Priligy.