Lansoprazole orodispersible Tablets

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Lansoprazole orodispersible tablets contain the same active ingredient as standard Lansoprazole capsules but are designed to dissolve before swallowing. They can be placed on the tongue to dissolve or dispersed in water. Suitable for patients with dysphagia, older adults, or those who simply prefer not to swallow standard capsules. Equally effective as capsule formulations.

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Additional information

Strength

15mg, 30mg

Quantity

28, 56

Overview

Content Written by:

Hanifa Tai
Role: Pharmacist & Content Writer
GPhC Number: 2074961
Content Published: 01/04/2026
Next Review: 01/04/2027

Medically Reviewed by:

Farzin Ghayedy
Role: Pharmacist
GPhC Number: 2218065
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Description

What Are Lansoprazole Orodispersible Tablets?

Lansoprazole orodispersible tablets contain gastro-resistant microgranules that dissolve in the mouth or when mixed with water. They reduce stomach acid production in exactly the same way as standard capsules. The key difference is the way you take them — they do not need to be swallowed whole.

Who Is This Formulation Suitable For?

Orodispersible tablets may be appropriate for: patients with dysphagia (swallowing difficulties), older adults who prefer a dissolvable option, patients requiring administration via feeding tube (under clinical supervision), and individuals who find capsules uncomfortable. If you can swallow standard capsules comfortably, those may also be suitable and are often a lower-cost option.

How to Take Lansoprazole Orodispersible Tablets

Place the tablet on the tongue and allow it to disperse before swallowing. Alternatively, disperse in approximately 10ml of water, stir gently and drink immediately. Do not crush or chew the microgranules. Take once daily, 30–60 minutes before food.

How It Works

Like all PPIs, Lansoprazole blocks proton pumps in the stomach lining. Acid reduction begins within 1–2 hours. Full therapeutic benefit develops over several days of regular use. Effectiveness is identical to standard capsule formulations.

Lansoprazole vs Omeprazole vs Famotidine

Both Lansoprazole and Omeprazole are PPIs providing sustained acid suppression. Individual patients may respond better to one than the other. Famotidine works via a different mechanism and provides shorter-duration acid reduction but faster onset. Your pharmacist will determine the most appropriate option for your symptoms and history.

FAQ

Q: Do orodispersible tablets work the same as capsules?

A: Yes. They contain the same active ingredient and provide identical acid suppression. The only difference is the formulation and how they are taken.

Q: Can I swallow the tablet whole rather than dissolving it?

A: These tablets are specifically designed to be dissolved — either on the tongue or in water. Swallowing them whole is not recommended as they work best when dispersed as intended.

Q: How long does treatment last?

A: For reflux, a typical course lasts 4–8 weeks. Shorter initial courses of 14–28 days may be provided via online pharmacisting. Persistent or worsening symptoms require further medical review.

Q: Are the side effects the same as standard capsules?

A: Yes. The side effects are the same as for standard Lansoprazole capsules — headache, nausea, diarrhoea, and constipation are the most common. Serious reactions are rare.

Q: What medicines interact with Lansoprazole orodispersible tablets?

A: Interactions are the same as for standard Lansoprazole capsules — including methotrexate, warfarin, HIV medicines, and certain antifungals. Always disclose your full medication history in the consultation.

Side Effects

Common Side Effects

Usually mild and temporary:

  • Headache
  • Nausea
  • Diarrhoea
  • Constipation

Rare but Serious — Seek Urgent Medical Attention

  • Serious allergic reactions — seek urgent help
  • Significant skin reactions — seek urgent help

Do Not Take If You:

  • You are allergic to Lansoprazole or other PPIs
  • You have severe liver impairment
  • You have unexplained weight loss or difficulty swallowing
  • You show signs of gastrointestinal bleeding

Key Drug Interactions — Always Declare All Medicines:

  • Methotrexate
  • Warfarin
  • HIV medicines
  • Certain antifungals

Long-Term Safety Note: Prolonged PPI use may be associated with low magnesium levels, reduced vitamin B12 absorption, slightly increased fracture risk, and increased susceptibility to certain gut infections. These risks are generally small and more relevant with long-term high-dose use. Regular reviews help ensure continued need and safety.

Seek Urgent Medical Attention If You Develop: difficulty swallowing, vomiting blood, black or tarry stools, severe chest pain, or unexplained weight loss.