Orders placed after 2pm on Friday 22nd May will be dispatched on Tuesday 26th May due to the Bank Holiday.
Duraphat 5000 51g
£18.00
PharmaBee supplies Duraphat 5000ppm Fluoride Toothpaste (51g) — the highest-strength fluoride toothpaste available on prescription in the UK. Supplied following a secure online consultation reviewed by our team. No dental surgery visit is required.
Duraphat 5000ppm is designed for adults at high risk of dental decay and provides significantly enhanced protection compared with standard toothpaste. It is not a cosmetic product and is not a whitening toothpaste.
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Additional information
| Quantity | 51g |
|---|
Overview
Content Written by:
Hanifa Tai
Hanifa Tai
Role: Pharmacist & Content Writer
GPhC Number: 2074961
Content Published: 01/04/2026
Next Review: 01/04/2027
Description
What Is Duraphat 5000?
Duraphat 5000 contains 5000 parts per million (ppm) fluoride. Standard adult toothpaste contains 1350–1450ppm, and Duraphat 2800 contains 2800ppm — making Duraphat 5000 the strongest fluoride toothpaste available in the UK on prescription.
Fluoride works by:
- Strengthening tooth enamel
- Promoting remineralisation of early enamel damage
- Reducing acid production by bacteria
- Making teeth more resistant to decay
Duraphat 5000 is used for prevention of dental caries in high-risk adults, remineralisation of early enamel lesions, treatment of dentine hypersensitivity, protection of exposed root surfaces, patients with reduced saliva flow (dry mouth), and patients undergoing radiotherapy affecting the head or neck.
Who Is Duraphat 5000 Suitable For?
Duraphat 5000 may be appropriate for adults aged 16 years and over with:
- Multiple active cavities
- A history of severe dental decay
- Recurrent decay despite standard fluoride use
- Dry mouth (xerostomia)
- Exposed dentine or root surfaces
- Radiotherapy to the head or neck
How to Use Duraphat 5000
Duraphat 5000 replaces your normal toothpaste.
- Apply a pea-sized amount to a clean toothbrush
- Brush thoroughly twice daily (morning and evening)
- Spit out after brushing
- Do not rinse with water
- Do not eat or drink for at least 30 minutes
Not rinsing allows the fluoride to remain in contact with enamel for longer, increasing its protective effect. Do not swallow the toothpaste. Keep out of reach of children.
Difference Between Duraphat 2800 and Duraphat 5000
Duraphat 2800 contains 2800ppm fluoride while Duraphat 5000 contains 5000ppm fluoride — almost double the concentration. Duraphat 5000 is typically reserved for patients at higher risk of decay or those who have not responded adequately to lower-strength products.
FAQ
Is Duraphat 5000 the strongest toothpaste available?
Yes. It contains 5000ppm fluoride and is the highest strength available on prescription in the UK.
Can I use it instead of my normal toothpaste?
Yes. It replaces your regular toothpaste entirely.
Can children use it?
It is generally intended for patients aged 16 and over unless specifically directed by a dental professional.
Can I swallow it?
No. Always spit out thoroughly after brushing.
How quickly will I see results?
Protection builds gradually with consistent use. It is preventative and supports long-term enamel strength.
Can it be used during pregnancy or breastfeeding?
Fluoride toothpaste is generally considered safe during pregnancy and breastfeeding when used as directed. Systemic absorption from toothpaste is minimal when not swallowed. Declare this during your consultation so your pharmacist can confirm suitability.
Side Effects
Common Side Effects
Duraphat 5000 is generally well tolerated. Occasional side effects may include:
- Mild gum irritation
- Mouth soreness
- Temporary sensitivity
Rare Side Effects
Rarely, allergic reactions may occur. Stop use and seek medical advice if you experience any swelling of lips, face, or throat, a rash, or breathing difficulty. Side effects can be reported via the Yellow Card Scheme operated by the Medicines and Healthcare products Regulatory Agency.
